Reactions between Aromatic Aldehydes and α-Amino Acids. VII

On the Mechanism of Metabolic Reactions of Amino Acids Catalyzed by Vitamin B6 and Related Aldehydes

M. Breza Faculty of Chemical Technology, Slovak Technical University, Radlinskeho 9, 812 37 Bratislava, Slovak Republic Z. Naturforsch. 49c, 571-578 (1994); received April 25, 1994 [(N-salicylidene-D,L-glutamato)(pyridine)]copper(II), Crystal Structure, INDO/2 Charges, Metabolic Reactions of Amino Acids, Vitamin B6 Catalysis, Reaction Mechanism The crystal structure of [(N-salicylidene-D,L-glut...

A metabolic relationship between the aromatic amino acids.

Reaction of benzoylpyruvate with a mixture of aromatic aldehydes and 5-amino-1,3,4-thiadizole-2-thiol

Reactions of benzoylpyruvate with a mixture of aromatic aldehydes and 5-amino-1,3,4-thiadizole-2-thiol in a 1:1:1 molar ratio, afforded 5-(5-aryl-4-benzoyl-3-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-1,3,4-thiadizole-2-thiols (3a-c). The structure of the resulted products was confirmed by determination of the melting point and spectrophotometric techniques such as IR and 1H-NMR spectroscopy.

Metabolism of aromatic amino acids and amines.

Phosphotungstic Acidcatalyzed Strecker Three-Component Reaction of Amino Acids, Aldehydes, and Trimethylsilyl Cyanide

A simple and efficient one-pot, three-component Strecker reaction of protected amino acids, aromatic aldehydes, and trimethylsilyl cyanide has been developed for the synthesis of chiral α-amino nitriles. The reaction was carried out in the presence of catalytic amount of phosphotungstic acid (H3[P(W3O10)4]) as an environmentally friendly cata...